Should Patients with Schizophrenia be Treated with Antipsychotics Forever?

A Finnish registry study examined the risk of rehospitalization or death in almost 9000 patients with the first episode of schizophrenia over an observation period of 20 years.

IQWiG: Indication of an Added Benefit of Cariprazine

The Institute for Quality and Efficiency in Health Care (IQWiG) on July 16, 2018, published its opinion on cariprazine as part of its „benefit assessment“. It concludes that there is an “indication” that cariprazine has a “non-quantifiable added benefit” in the group of patients with schizophrenia with predominant negative symptoms.

Finally: A New Psychotropic Drug in Germany – Cariprazine

Recordati launched the new antipsychotic cariprazine in Germany in Mid-April. The benefit assessment by the G-BA has therefore started.

Antipsychotics for long-term treatment – when to stop? Or better not?

A new publication in the prestigious Lancet Psychiatry seems to provide new evidence for the benefits of long-term antipsychotic maintenance treatment in schizophrenia (Hui et al., Lancet Psychiatry 2018). On closer inspection, however, the paper confuses more than it provides new insights.

Cariprazine: the next touchstone for the German AMNOG

The interesting new antipsychotic compound cariprazine was recently approved by the European Medicines Agency (EMA). Its launch in Germany will be a new touchstone for the German Act on the Reform of the Market for Medicinal Products (AMNOG).